聴性脳幹反応と頭蓋内圧

概要

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The relationship between the auditory brainstem response (ABR) and the intracranial pressure (ICP) was studied in 35 comatose patients. The interwave latency between wave I to V of the ABR was not affected by the acute ICP changes. The amplitude ratio of waves V to I was also not influenced by the ICP changes. However, the ABR morphology in the patients who continuously showed high ICP (30mmHg or more) gradually deteriorated as time passed, even though it had been normal in the early stages; and some waves, wave I, for example, disappeared and finally no response was produced. The outcome of the patients who had high ICP (30mmHg or more) or who exhibited wave disappearance in ABR, whether partial or total disappearance, was very poor or death.Thus, we concluded that the ABR could not be influenced by acute changes of the ICP, but it could be affected by the continuation of high ICP which caused circulatory disturbance and/or herniation of the brain and induced brainstem damage secondarily.
耳鼻咽喉科臨床学会の論文