デンシトメ-タ-による上顎洞陰影の定量的測定--塩化リゾチ-ム大量投与の効果

概要

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X-ray opacity of the maxillary sinuses were evaluated using a densitometer in patients with chronic sinusitis whose subjective complaints and local findings of the nasal cavity were improved by massive dose administration of lysozyme (540mg/day).X-ray films of the waters view were used for the following analysis. The density of the middle points within the orbita was used as the index of the orbital density. The density of the trisected points within the maxillary sinus was used as the index of the maxillary density. The remainder of these two indices was calculated to facilitate the comparison within a subject. The sets of data were compared between pre- and post-treatment. As a result of the densitometric estimation of the film, it was objectively shown that massive dose administration of lysozyme was significantly effective for chronic sinusitis.Densitometric analysis of film minimizes the errors caused by radiographic conditions and subjective variations among the examiners. It is an excellent and useful method for quantitative evaluation of the therapeutic effect within a subject.
耳鼻咽喉科臨床学会の論文