グリセロ-ルの蝸牛電気現象に及ぼす影響 (前庭機能異常の研究-3-<特集>)

概要

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To study the rationale of the glycerol test, cochlear potentials were measured in albino guinea pigs after intravenous administration of 50% glycerol solution. The endocochlear dc potential was reduced slightly within a few minutes after glycerol injection and the negative summating potential also decreased simultaneously. However, these changes were merely transient and almost disappeared within ten minutes. Several investigators have pointed out that the reduction of inner ear pressure caused by glycerol injection takes place after about ten minutes. Therefore, it may be that the changes observed in this study are not due to dehydration by glycerol in the cochlea and, in turn, that the osmotic force of glycerol does not affect directly cochlear potentials, at least in normal guinea pigs.
耳鼻咽喉科臨床学会の論文