頭蓋内進展を認めた篩骨洞神経鞘腫症例

概要

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Neurinoma originating in the nasal cavity and paranasal sinuses is rare. We had a patient with a neurinoma arising from the ethmoid sinus and extending into the anterior cranial fossa. A 45-year-old woman was admitted to the Department of Otolaryngology of the National Defense Medical College with the chief complaint of right nasal obstruction. Anterior rhinoscopy showed a necrotic mass filling the anterior part of the nasal cavity. Biopsy from the surface of the mass revealed histological features suggestive of neurinoma. Under general anesthesia, Denker's operation was performed to extirpate the neoplasm. However, the tumor extended into the anterior cranial fossa and could not be removed because it was firmly adherent to the dura. The remainder of the neoplasm was removed completely through a frontal cranial approach and a lateral rhinotomy approach. The histological section of the tumor showed a typical neurinoma, demonstrating Antoni A and B types of cell pattern.
耳鼻咽喉科臨床学会の論文