アレルギ-性鼻炎患者における高IgE血症のin vitroにおける免疫担当細胞の機能測定

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概要

• 論文の詳細を見る

• It was found that pokeweed mitogen (PWM) generated helper T cell function, and Concanavalin A (Con A) generated suppressor T cell function for IgE production in a human peripheral T-B cell co-culture system. This assay system provides useful information for estimating the regulatory function for IgE production of human T cells in several allergic diseases. With this system, the quantitive activity of helper T cell and suppressor T cell function was measured in patients with allergic rhinitis. It was found that helper T cell function was enhanced and suppressor T cell function suppressed in these patients. Hyper IgE Nemia in these patients was probably due to the reciprocal action of increasing functional activity of helper T cells and decreasing functional activity of suppressor T cells.

• 耳鼻咽喉科臨床学会の論文

著者

• 西澤 芳男

  豊中診療所内科

• 西澤 芳男

  豊中診療所

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