In Vivo Action of Pronase-P:(Pathological review)

概要

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The pathological and pathohistological studies were made of the influences of Pronase-P upon the chronic inflammation of the paranasal sinusitis. And as the result it can be concluded that the recovery of chronic inflammation was promoted by oral administration of pronase-P. The several of the main findings were as follows:A. macroscopic findings1) decrease of pus and mucous.2) gradual improvement of inflammatous changes. (such as thicking of mucosus membrane) of sinus.B. histological findings1) improvement of edema, infiltration of rund cells, new growth of capillaries.2) f ibrolisis in connective tissue.3) increase of mucopolysaccharides in the ground substance of mucous membrane especially around capillaries.
耳鼻咽喉科臨床学会の論文