A Study on the Function of the Nasal Mucous
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概要
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The nasal cavity, which walls are covered with special type of mucous tissues that differs much from mucous of other part of the body, perfoms its function as the gate of respiratory tract by incessant changes of its volumen physiologically. It is evident that the volumen of nasal cavity is influenced lay humidity and temperature of the air and other physical conditions or by medicins applied. The anther tried experiments on these relations by using cats and rabbits. The following is brief outline of the results.<BR>1. Being punctured cat in its frontal sinus, and abbits in their ethmoid cells both on the face, medicine was dropped into them to fill up the whole nasal cavity. Some animals were put under narcosis, some others were stimulated electrically on their nervous sympathetics in the neck or extirpated their upper ganglion. Changes of the volumen of nasal cavity in all these cases are observed measuring the number and frequency of liquid drops from the nostrile.<BR>2. When fluid of physiological common salt at constant temperature is infused into the frontal sinus or into the ethmoid cells, it bigins to drip from the nares, at first irregularly in quantity and number of drips, two or three inutes later, however, it becomes regular and continues the same condition for a long time.<BR>3. When 3 c.c. of 3 % Cocain hydrochrolicum solution or 3 c.c. of 0.01% Adrenalin solution is applied on the mucous of the nasal cavity, it shows that both solution act to enlarge the nasal cavity, the former enlarges it about 13, 5% and the latter about 11, 5%.<BR>4. The solution of Butynoloil, of 3% Chinin hydrochrolicum and of 5% Butyn make the nasal cavity narrower. 5% Butyn solution acts most effectively and chinin hydrochrolicum second of it, e. i. 1% Butyn narrows the nasal cavity about 11%, 3% Chinin hydrochrolicum about 16%, and 5% Butyn about 50%.<BR>5. 5 c. c. of 5% Protargol solution acts on the nasal cavity to be narrowed about 25% after twenty minutes it was applied.<BR>6. The mixed solution of 0, 001% Adrenalin and 0.01% Cocain enlarges the nasal cavity in degree of 20%, ten minutes after it was applied and continues that condition about thirty minutes.<BR>7. Narcosis with chroloform causes narrowness of the nasal cavity about 22%, but at awaking the volumen of the nasal cavity inclines to get back to its usual condition showing the irregular drips and confusion of their numbers.<BR>8. Solution of the physiological common salt at 40°C. causes a slight enlargment to the nasal cavity, during the same solution at 10°C. remarkably narrows the cavity. The former shows 16% of enlargment and the latter 19% of narrowness.<BR>9. A definite electric stimlation of the sympathetic nerve in the neck causes about 10% enlargment of the cavity and it causes about 15% narrowness when the upper ganglion is extirpated.
- 耳鼻咽喉科臨床学会の論文