Artificial endocrine pancreas with computer algorithm for self-adaptive control of blood glucose concentration

概要

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Computer algorithm for self-adaptive control of blood glucose has been established.With this algorithm, parameters deciding insulin infusion rate are automatically changed in accordance with insulin sensitivity index of the subjects calculated from the difference between the measured rate of change in blood glucose and the projected rate of change in blood glucose.The validity of this algorithm was recognized in animal experiments using depancreatized dogs.Artificial endocrine pancreas with selfadaptive algorithm is useful not only as the management of diabetics but also as the elegant research tool for the investigation of insulin sensitivity of the diabetics or. analyzing the blood glucose regulatory mechanism
一般社団法人日本人工臓器学会の論文