Osteoinductivity of CO3 apatite-collagen composites.
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概要
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CO3 apatites with chemical compositions and crystallographic properties similar to those of bone was mixed with 0.5wt% collagen solution. The composites 4hr-UV-irradiated and incubated in 0.9% NaCl solution at 37°C were less deformed than non-UV-irradiated samples, under a compressive force. The biocompatibility of the composites with surrounding tissues seemed to be good, under the periosteum cranii of rats and rabbits. The composites treated with fibrin glue in addition to the UV-irradiation kept their shape even after 1-month-implantation. The newly synthesized bone-like substance was observed on the bone facing to the composite.
- 一般社団法人 日本人工臓器学会の論文