Effect of Recombinant Erythropoietin on Autologous Blood Predeposit before Elective Surgery of Hip.

概要

論文の詳細を見る
The cases of seventeen patients who had spherical acetabular osteotomy mainly were reviewed to evaluate the efficacy of recombinant human erythropoietin (EPO) in autologous blood predeposit, compared with the control group of nineteen patients. Autologous blood predeposit was performed by leap-frog method, and EPO was intravenously administered two times a week from a week before the first phlebotomy to the operation. The mean age of the EPO group was 44.6 years and the control group 34.4 yeras. The mean amount of autologous blood predeposit and perioperative blood loss of each group were 1447g, 1368g and 1507g, 1114g.The rate of reduction of the blood hemoglobin concentration of the EPO group was significantly less than that of the control group (P<0.001), and no side effect appeared. And in the patients of the EPO group the rate of reduction of blood hemoglobin concentration was related to the serum iron and the serum ferritin. In conclusion, EPO is effective to the autologous blood predeposit before elective operations with enough iron supply.
西日本整形・災害外科学会の論文