コイとマダイの各組織に対するCdの蓄積の比較〔英文〕
スポンサーリンク
概要
- 論文の詳細を見る
Carp and red sea bream were exposed for 96h to 0.3mgCd/l in freshwater and 10mgCd/l in seawater, respectively. The cadmium tissue distributions and cadmium cytosolic partitioning in tissues were analyzed using Sephadex G-75 chromatography to estimate the toxicity in tissues. Cadmium tissue distributions in carp and red sea bream after intraperitoneal administrations of CdCl2 and cadmium-metallothionein (CdMT) were also investigated to compare the cadmium movement in their bodies. The exposure of carp to cadmium resulted in the highest accumulation in the gills, followed in descending order by the kidney, intestine, and hepatopancreas. The highest proportion of cadmium concentration in the HMW pool (fractions containing enzymes) relative to the MMW pool (fractions containing metallothionein) was found in the gills. These results suggest that the gills of carp are most likely to be harmfully affected by exposure to an acute level of cadmium. The exposure of red sea bream to cadmium resulted in the highest accumlation in the liver, followed in descending order by the kidney, intestine, and gills. The cadmium concentration in the HMW pool was highest in the kidney. However, the highest proportion of cadmium concentration in the HMW pool relative to the MMW pool was found in the intestine. These results suggest that the maximum detoxification capacity was reached first in the intestine. After the intraperitoneal administration of CdMT, a significantly high accumulation of cadmium was found in the kidney of carp but not in the kidney of red sea bream. This result suggests that the ability to trap the cadmium bound to MT in plasma by kidney may be lower in red sea bream than in carp. In conclusion, the osmotic regulation mechanisms in fish may possibly be related to the distribution and movement of cadmium in the body.
- 日本水産學會の論文