一定薬物の作用と副腎中のAdrenalin及びNoradrenalinの産生について

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概要

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• The investigation on the amounts of adrenaline (A) and <I>nor</I>adrenaline (N) in the suprarenal gland and in the blood after administration of mecholyl, acetylcholine, nicotine and the splanchnic stimulation was performed. Rat's blood-pressure and rabbit's intestine were used to estimate the contents of A and N in the isolated rabbit's suprarenal gland, the Gaddum's formula being applied for calculation. The proportions of A and N liberated from the suprarenal gland were determined by the method. of Bülbring and Burn, using a denervated cat's nictitating membranes. Under the conditions mentioned above an increase of N and a decrease of A was observed. From these results it may be considered that N plays an important part as an adrenergic transmitter.

• 社団法人 日本薬理学会の論文

著者

• 瀬川 富郎

  京都大學醫學部藥理學教室

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