Experimental studies on poisoning of aromatic amino- and nitro-compounds:VII. On the mechanism of methemoglobin formation
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Methemoglobin formation after the aromatic amino- or nitro-compounds was proved by the spectroscopic investigations following with the lapse of time of observations and its mechanism was explained on the basis of electrotonic theory with reference to the literatures of other authors ever published. On his opinion Fe··in hemoglobin will be oxidized to Fe··· directly or indirectly due to the electrotonic potency of available drugs tested and thus methemoglobin will be formed by neutralization of the increased charges of Fe ion with OH<SUP>-</SUP> in the solution.
- 社団法人 日本薬理学会の論文
社団法人 日本薬理学会 | 論文
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