クリック型反応の新展開 : —ペプチドケミストリーへの応用—

概要

論文の詳細を見る
“Click Chemistry” is a chemical concept proposed by Prof. Sharpless in 2001. Notable advantages of click reactions are their high level of efficiency, stereospecificity, atom economy, and functionality tolerances. A large number of examples have been reported in this decade due to the usefulness of click reactions. While Huisgen reaction is the most representative example in this field, they have gradually been expanded to a variety of reactions and utilized for bioconjugations and peptide syntheses.