Analysis of Polypharmacy-Structure of Chinese Medical Prescription (II):Concerning "Shimotsu-to rui"

概要

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The group of 12 "Shimotsu-to rui" chinese medical prescriptions containing Angelica acutiloba Kitag., Cnidium officinale Mak., Paeonia lactiflora Pall. and Rehmannia glutinosa (Gaertn.) Libosch were analysed by multiple dimensional scaling analysis (M-D-SCAL), quantification of the third type (QT-III) and cluster analysis (C.A.). M-D-SCAL were carried out in 2 ways, by that of the angle method and the Jaccard's coefficient. Using the angle method in analysing the 12 prescriptions, the "Orengedoku-to" groups and the diuretic & peptic prescription groups were clarified and some prescriptions containing specific herbs were located in a marginal region, and these locations were fit for traditional information. QT-III gave a simular location of the prescriptions to the result of the M-D-SCAL with Jaccard's coefficient. In this method, not only the prescriptions, but also the herbs simultaneously can be located. This made possible the interpretation of the intra-relations between the 12 prescriptions, in terms of the axis pertaining to the herbs. Certain herbs consistently fall into the same categorical region, indicating a shared relationship and corresponding to the traditionally conceived "Yaku-tsui" or "paired herbs".
社団法人日本東洋医学会の論文