健常若年女性に発症し, シプロフロキサシンなどによる治療が奏功したMycobacterium fortuitum肺感染症の1例

概要

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A 22 year-old woman was admitted to our hospital complaining of subtle fever andproductive cough. She did not smoke and had no underlying disease. Her chest radiographshowed infilltration in the right upper lung field. A diagnosis of Mycobacterium fortuitumpulmonary disease was made on the basis of isolation of M. fortuitum from repeatedsputum cultures. On admission, we administered standard antimycobacterial agents, butfound the M. fortuitum isolated in this case to be completely resistant to them. We thenadministered antibiotics including 600mg of ciprofloxacin and 200mg of doxycycline. Thepneumonic findings on chest X-ray and her clinical symptoms gradually improvedthereafter. The in vitro susceptibility tests confirmed the efficacy of ciprofloxacin anddoxycycline. We concluded that these drugs contributed significantly to improve the disease.