Mycobacteria Nicotinamide adenine dinucleotide nucleosidase (Report I: Distribution of the Enzyme)

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概要

• 論文の詳細を見る

• Distribution of NAD-ase and its inhibitor in myco- bacteria was studied." Heat-activated" NAD-ase was found only in <I>Mycob. butyricum</I> and <I>Mycob. avium</I>. Heat-labile NAD-ase inhibitor had the same distribution pattern in mycobacteria.<BR>In the case of the isoniazid-resistant variants of the above strains, the enzyme-activity was revealed only in the heat-treated cell-free extract, and not in the heat-treated cell-suspension.<BR>The anzyme-inhibitor relationship was absolutely specific.<BR>Isoniazid-analogue formation hypothesis for the action mechanism of isoniazid was discussed as having some difficulties.

• 一般社団法人 日本結核病学会の論文

著者

• 戸井田 一郎

  財団法人結核予防会結核研究所

• 山本 節子

  財団法人結核予防会結核研究所

関連論文

• 結核菌の基礎的研究
• Mycobacteria Nicotinamide adenine dinucleotide nucleosidase (Report I: Distribution of the Enzyme)

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