抗酸菌の溶原化に関する研究 : 第1報 Y13ファージによる抗酸菌獣調株の溶原化
スポンサーリンク
概要
- 論文の詳細を見る
Lysogenization rates of Mycobacteriaby mycobacteriophageswere investigated using the systems of the rapidly growing Mycobacterium, strain Jucho, and the two phages, Y 13-L and-S. Changes of bacterial characters accompanied with the lysogenization, especially phage susceptibilities and sugar availabilities, were also studied.<BR>The lysogenization rate by Y 13 S was high, 27 %, and that by Y 13 L was rather low, 4.3 %. It was shown that the phage spontaneously released from the bacterium previously lysogenized by Y 13 L, was more temperate than the original with a higher lysogenization rate of 31-47 %.<BR>The rate of spontaneous phage release of Myc. jucho (Y 13 L) was 3.5 ×10<SUP>-1</SUP> and that of Myc. jucho (Y 13 S) was 1.1×10<SUP>-3</SUP>.<BR>The host range was studied comparatively between the orginal Y 13 L phage and its more temperate one described above, against 119 strains of rapidly growing Mycobacteria, using the RTD spot technique, and only slight differences were observed.<BR>Following changes in the phage susceptibilities of the lysogenized Mycobacteria from that of the original one were observed: Myc. jucho (Y 13 L) was resistant to the phage A 6 and D 4, and Myc. jucho (Y 13 S) was partially resistant to the phage HC, though the original strain was sensitive to those phages. Neutralization test by anti-phage sera has shown the closed relation among Y 13 L, A 6 and D 4 and between Y 13 S and HC, respectively.<BR>Acid production patterns from carbohydrates of the lysogenized mycobacteria showed no differnce from those of the original.<BR>Attempts of the phage induction of the lysogenized bacteria employing UV irradiation were carried out with no success.
- 日本細菌学会の論文
著者
関連論文
- 抗酸菌の溶原化に関する研究 : 第1報 Y13ファージによる抗酸菌獣調株の溶原化
- 抗酸菌の溶原化に関する研究 : 第2報 Y13L溶原獣調の示すautoplaqueとdismune現象
- 溶原性抗酸菌の誘発に関する研究
- 抗酸菌フアージの吸着に関する研究 : (第2報) 流産感染と宿主殺菌効果
- 抗酸菌フアージの吸着に関する研究 : (第1報) 十二種の系におけるフアージ吸着率流産率, 増殖, およびそれらに対するTween 80の作用について