Effects of vitamin E in kid erythrocytes on Tween 20-induced hemolysis in vitro.
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概要
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Red blood cells (RBC) of alpha-tocopherol sufficiency and deficiency were produced in kids fed on purified diets to investigate the relationship between RBC alpha-tocopherol levels and hemolysis induced by Tween 20. RBC alpha-tocopherol contents of vitamin E-deficient kids were non-detectable from 4 weeks, and percentages of hemolysis increased to over 70%. A highly significant decrease in hemolysis was noted when vitamin E was added to the diet. Tween 20 hemolysis values were negatively correlated with RBC tocopherol levels in kids. The concentration of RBC alpha-tocopherol required to prevent the hemolysis was found to be 0.6 μg/ml packed cells.
- 財団法人 学会誌刊行センターの論文
著者
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浜田 龍夫
Department of Nutrition, National Institute of Animal Industry, Tsukuba Norindanchi
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甫立 京子
Department of Nutrition, National Institute of Animal Industry, Tsukuba Norindanchi