The Large Intestine Compensates for Insufficient Calcium Absorption in the Small Intestine in Rats
スポンサーリンク
概要
- 論文の詳細を見る
We previously demonstrated that the large intestine com-pensated for decreased calcium (Ca) absorption caused by renal failure in rats fed a highly fermentable dietary fiber. In this study, we examined whether the large intestine compensated for insufficient Ca absorption in the rat small intestine without ingestion of a fermentable dietary fiber. Rats were fed one of four test diets containing either insoluble (carbonate) or soluble (gluconate, lactate, or citrate) Ca sources. The dietary Ca level was 2.0g/kg, which is lower than the minimum requirement for rats (3.0g/kg), to conduct the present study under a condition in which rats can maximally absorb Ca. To prevent Ca absorption in the small intestine, we replaced a primary phosphate (KH2PO4) with secondary phosphates (K2HPO4 and Na2HPO4) in diets. The apparent Ca absorption in the small intestine was estimated by adding chromic oxide (Cr2O3) as an insoluble and an unabsorbed marker to test diets and by measuring the ratio of Ca:Cr in the cecal content. The apparent Ca absorption in the whole intestine was estimated by the intake and fecal excretion of Ca. The apparent Ca absorption in the small intestine was significantly lower from the Ca carbonate diet than from the Ca gluconate, lactate, or citrate diets. The apparent Ca absorption in the whole intestine was not significantly different among the four groups, and the values were similar to the absorption rates in the small intestines of rats fed diets containing soluble Ca sources. These results show the following: (a) In rats fed 0.2% Ca diets containing soluble Ca salts, Ca is mostly absorbed in the small intestine, even in secondary phosphate intakes; (b) In contrast, in rats fed a 0.2% Ca diet containing an insoluble Ca salt (carbonate), Ca is not sufficiently absorbed in the small intestine. However, the large intestine compensates for the small intestinal Ca absorption decreased by dietary secondary phosphates.
- 財団法人 学会誌刊行センターの論文
著者
-
Kasai Takanori
Laboratory Of Food Biochemistry Department Of Bioscience And Chemistry Faculty Of Agriculture Hokkai
-
Hara Hiroshi
Laboratory Of Nutritional Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture
-
SHIGA Kazuki
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agricultu
-
HARA Hiroshi
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agriculture
-
SHIGA Kazuki
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agriculture
-
KASAI Takanori
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agriculture
関連論文
- Effects of difructose anhydride III (DFA III) administration on rat intestinal microbiota.
- A soluble flavonoid-glycoside, alphaG-rutin, is absorbed as glycosides in the isolated gastric and intestinal mucosa.
- Inhibitory Effects of Ellagi- and Gallotannins on Rat Intestinal α-Glucosidase Complexes
- α-Glucosidase Inhibitors from Clove (Syzgium aromaticum)
- Structure-activity Relationships for α-Glucosidase Inhibition of Baicalein, 5,6,7-Trihydroxyflavone : the Effect of A-Ring Substitution
- 6-Hydroxyflavonoids as α-Glucosidase Inhibitors from Marjoram (Origanum majorana) Leaves(Food & Nutrition Science)
- Quinone Hemiacetal Formation from Protocatechuic Acid during the DPPH Radical Scavenging Reaction(Organic Chemistry)
- Acetyl-CoA Carboxylase Inhibitors from Avocado (Persea americana Mill) Fruits(Food & Nutrition Science)
- Effects of DFA IV in Rats : Calcium Absorption and Metabolism of DFA IV by Intestinal Microorganisms
- Apolipoprotein B mRNA Editing in the Liver and Small Intestine of Rats Fed on Beet Fiber, Soy Protein, and Fish Oil.
- Non-effect of hexamethonium, a ganglionic blocker, on the response of ileal apolipoprotein A-IV mRNA following a massive small bowel resection in rats
- Hibiscus Acid as an Inhibitor of Starch Digestion in the Caco-2 Cell Model System(Food & Nutrition Science)
- α-Amylase Inhibitors from Roselle (Hibiscus sabdariffa Linn.) Tea
- Development of a Method for the Identification of S-IgA-Coated Bacterial Composition in Mouse and Human Feces
- Voluntary Running Exercise Alters Microbiota Composition and Increases n-Butyrate Concentration in the Rat Cecum
- Improved Isolation Methods for Mucosal Leukocytes from Small and Large Intestines in Rats
- High Biliary Excretion Levels of Quercetin Metabolites after Administration of a Quercetin Glycoside in Conscious Bile Duct Cannulated Rats
- Adrenaline-Induced Lipolysis in Isolated Rat Mesenteric Adipocytes Is Higher in the Large Intestine Than in the Small Intestine
- Improvement of Bone Strength and Dermal Thickness Due to Dietary Edible Bird's Nest Extract in Ovariectomized Rats
- The Large Intestine Compensates for Insufficient Calcium Absorption in the Small Intestine in Rats
- Dietary Wheat Bran Modulates Proliferating Cell Nuclear Antigen-Labeling Index of the Rat Colorectum after Treatment with 1, 2-Dimethylhydrazine
- Administration of Anti-Asialo GM1 Serum Increases Aberrant Crypt Foci Induced by 1, 2-Dimethylhydrazine in the Large Bowel of Rats
- Supplementation of Methionine to a Low Soybean Protein Diet Strikingly Increases Pancreatic Amylase Activity in Rats