Selenium Levels and Glutathione Peroxidase Activities in Blood in an Andean High-Altitude Population.

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概要

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• Selenium (Se) levels in blood (whole blood, erythrocytes and serum) and blood glutathione peroxidase (GSH-Px) activity were investigated in people living at high altitude in Bolivia (4, 000m above sea level). These parameters were compared to those of people living at low altitude (300m above sea level). The Se levels in whole blood of the high-altitude subjects did not differ significantly from those of the low-altitude subjects. However, the Se levels in erythrocytes were significantly lower in the high-altitude subjects than in the low-altitude subjects, whereas serum Se levels were higher in the high-altitude subjects than in the low-altitude subjects. GSH-Px activity (Unit/g Hb) was significantly lower in the high-altitude subjects than in the low-altitude subjects. The mean corpuscular Hb concentration (MCHC), an indicator of the age of erythrocytes, in the high-altitude subjects was significantly higher than in the low-altitude subjects. These results show that the GSH-Px activity in the blood of the high-altitude subjects is relatively low. This may be due to their aged erythrocytes and/or to relatively low Se intake in the high-altitude population compared with low-altitude population.

• 財団法人 学会誌刊行センターの論文

著者

• Takemoto Tai-ichiro

  Department of Health and Nutrition, Faculty of Health Management, Nagasaki International University

• MOJI KAZUHIKO

  Department of Public Health, School of Medicine, Nagasaki University

• Watanabe Chiho

  Department Of Environmental Health Sciences Tohoku University School Of Medicine

• KIM She-Whan

  Department of Physical Science of Kang won National University

• Himeno Seiichiro

  Department Of Human Ecology School Of Health Sciences Faculty Of Medicine University Of Tokyo

• Suzuki Tsuguyoshi

  Department Of Human Ecology School Of Health Sciences Faculty Of Medicine University Of Tokyo

• KASHIWAZAKI Hiroshi

  Department of Human Sciences, School of Health Sciences, University of Occupational and Environmenta

• IMAI Hideki

  Regional Environment Division, National Institute for Environmental Studies

• KAEUTO Michinori

  Department of Human Ecology, School of International Health, University of Tokyo

• RIVERA José

  Hospital Virgen de Copacabana, La Paz

• HIMENO Seiichiro

  Department of Public Health, School of Pharmaceutical Sciences, Kitasato University

• KIM She-Whan

  Department of Physical Education, College of Education, Kangweon University

• TAKEMOTO Tai-ichiro

  Department of Public Health, School of Medicine, Nagasaki University

• SUZUKI Tsuguyoshi

  Department of Human Ecology, School of International Health, University of Tokyo

• KASHIWAZAKI Hiroshi

  Department of Human Ecology, School of International Health, University of Tokyo

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