幼児顎下部に発生した侵襲性線維腫症の1例

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An aggressive fibromatosis is a tumor-like fibrous lesion, and it resembles a welldifferenciated fibrosarcoma histologically. It is clinically aggressive to the surrounding tissues, but has no metastasizing ability. This report presents a rare case of an aggressive fibromatosis involving the inferior border of an infant mandible. A three-year-old girl first visited the First Department of Oral Surgery, Tokyo Medical and Dental University, on April 26th, 1982. At that time, a firm 35×45mm mass was found in the right submandibular region. The parents had found the painless mass in the left lower face of the patient November, 1981. At the first visit to our department, this mass showed cartilage-like hardness, and the demarcation of the mass was relatively definite but not tender. Submandibular lymph node was not palpable. Intraorally diffuse swelling was seen on the buccal site of the first and second deciduous molar region. Radiographically undermining bone defect was found at the lower border of the mandible beneath the second deciduous molar and the unerupted permanent first molar. By incisional biopsy the diagnosis of aggressive fibromatosis was made. On May 24 th, 1982, segmental resection of the mandible including the surrounding tissues, masseter muscle and submandibular gland was carried out. Examination of biopsy and surgical materials showed similar appearances. Tumor-like proliferation of fibrous tissues in the submandibular region invaded the cortex of the mandible and the periphery of the submandibular gland, but not into the bone marrow, the parenchyma inner portion of the submandibular gland, or the regional lymph node. Microscopic examination revealed cellular proliferation of elongated, spindle-shaped fibrocytes and fibroblasts with interlacing budles of collagen fibers. Cellular atypia was slight, and mitotic figure was little. There was no evidence of recurrence or metastasis in the patient for 2 years and 5 months after the operation.
社団法人日本口腔外科学会の論文

幼児顎下部に発生した侵襲性線維腫症の1例

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