口底と肝臓の重複癌の1症例ならびに本邦頭頸部領域重複癌の統計的観察

概要

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Since the first reported case of multiple primary carcinomas (Billroth 1869), this interesting condition has become more prevalent from year to year. We report a case of multiple primary carcinoma involving the oral floor and the liver in a 62-year-old male. This case satisfied diagnostic criteria of both Billroth as well as Warren and Gates. In addition we reviewed the Japanese literature from 1934 to 1986 which included 323 cases of multiple primary carcinoma involving the head and neck regions. (1) The average age of patients was 60.4 years, cases occurred most frequently during the 7 th to 8 th decade. (2) The ratio of males to females was 2.4:1. (3) Synchronous (within 6 months) carcinomas occurred in 42% of cases and metachronous was found in 58% of cases. (4) In multiple primary carcinomas of head and neck, carcinomas involving multiple different maxillary lesions were most frequent. (5) In cases of primary carcinoma of the head and neck involving other regions, the stomach and esophagus were most frequent sites. (6) The most common histologic type of neoplasms were squamous cell carcinoma. Both first and second cancers frequently well identified.