塩酸オキシテトラサイクリン歯科用円錐の臨床効果に対する二重盲検による検討

概要

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We investigated the clinical effects of an OTC dental cone (®Oxytetra Cone "Showa")(OTC-C), by the double blind method using an inactive placebo (P) and obtained the following results. 1. OTC-C was associated with significantly better postoperative granulation from 3 days after teeth extraction. 2. OTC-C resulted in significant reductiou of redness in the surrounding gingiva from 3 days after teeth extraction. 3. Final overall evaluation showed signification superiority of OTC-C, with an effectiveness rate of 92.8%for OTC-C and 60% for P. 4. The rate of usefulness was 89.3% for OTC-C and 63.3% for P, showing significantly high usefulness of OTC-C. 5. There were no side effects in any subject. 6. The higher usefulness of OTC-C was suggested in relation to greater operative stress including extraction of teeth associated with purulent inflammation and surgical duration. From the above findings, the superior usefulness of Oxytetra Cone "Showa" in clinical settings was confirmed. It seems necessary to take advantage of the dental cone particularly in patients with purulent inflammation or those who had systemic complications and in whom postoperative wound healing or influence on other distant organs is of concern.
社団法人日本口腔外科学会の論文