舌下面に生じたリンパ上皮性嚢胞の1例-特に免疫組織学的検索-

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We reported here a case of Lymphoepithelial cyst arising at the ventral surface of the tongue in a 34 year old male.<BR>Histopathological examination revealed that the cyst was composed of fibrous tissue, thin squamous epithelium and lymphoid tissue with a prominent germinal center. This case was considered to be a typical, oral lymphoepithelial cyst.<BR>We also examined the distribution of immunoglobulins, T and B cells and lysozyme.<BR>Immunohistological examination revealed that immunoglobulin-positive cells (IgG, IgA and IgM) were distributed between the lining epithelium and lymphoid tissue with a variation in number. Localization of lysozyme-positive cells was similar to that of immunoglobulin-positive cells. Similar to tonsil and lymph node, B cells were observed in the cap area and medulla of lymphoid tissue while decreased numbers of T cells were found in fibrous connective tissue beneath the lining epithelium.