唾液腺腫瘍105例の検討
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A total of 105 salivary gland tumors treated and followed up by our department from 1965 to 1987 were clinically studied. The results were as follows:<BR>1. There were 65 benign tumors (61.9%) and 40 malignant tumors (38.1%).<BR>2. Histologically, the tumors occurred in the following order of frequency: adenomaspleomorphic adenoma (52 cases), Warthin tumor (7 cases), oncocytoma (2 cases), basal cell adenoma (1 case) and cystadenoma (1 case); carcinomas-mucoepidermoid carcinoma (15 cases), adenoid cystic carcinoma (12 cases), carcinoma in pleomorphic adenoma (5 cases), adenocarcinoma (4 cases), squamous cell carcinoma (2 cases), acinic cell carcinoma (1 case) and epithelial-myoepithelial carcinoma (1 case); non-epithelial tumors-angioma (2 cases).<BR>3. The tumors originated from the major salivary glands in 32 cases and from the minor salivary glands in 73 cases. Among the cases that developed in the minor salivary glands, the most frequently affected site was the palate (45 cases), followed by the oral base (8 cases) and the buccal mucosa (7 cases).<BR>4. Clinical findings associated with a high incidence of malignancy were symptoms of pain and ulcers in addition to swelling at the first medical examination (75%). With respect to the primary site, the minor salivary glands except for the palate and lips had a high incidence of malignancy.<BR>5. Surgical treatment was performed for all benign tumors and 90% of the malignant tumors. In 70% of operated malignant tumors, radiotherapy and/or chemotherapy used concomitantly.<BR>6. The cumulative survival rate for all malignant cases was 78.9% at 5 years and 61.9% at 10 years. Histologically, mucoepidermoid carcinoma and carcinoma in pleomorphic adenoma had good prognoses, but adenoid cystic carcinoma, adenocarcinoma and squamous cell carcinoma had poor prognoses.<BR>7. Misdiagnoses were made before surgery in 3% of the benign tumors (2 cases) and in 30% of the malignant tumors (12 cases). Among the misdiagnosed malignant tumors 10 had no clinical findings indicative of malignancy and their prognoses were good. Two cases misdiagnosed as benign tumors had clinical findings of malignancy and their prognoses were poor.
- 社団法人 日本口腔外科学会の論文
社団法人 日本口腔外科学会 | 論文
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