モルフィセプチンの活性型立体配座I

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概要

• 論文の詳細を見る

• Conformational energy calculations were carried out on morphiceptin (Tyr-Pro-Phe-Pro-NH2) and its five active analogs. It was assumed that morphiceptin and its analogs would take a specific common 3-dimensional structure when they were bound to the receptor. Only two different low-energy conformers, A 70 and C 15, were found to be common throughout morphiceptin and its analogs. The results obtained here indicate that either A70 or C15 is the probable bioactive conformation of morphiceptin.

• 社団法人 日本農芸化学会の論文

著者

• 中馬 寛

  呉羽化学株式会社IDR開発室

関連論文

• モルフィセプチンの活性型立体配座I

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