Comparison of the Effects of Pantethine and Fursultiamine on Plasma Gastrointestinal Peptide Levels in Healthy Volunteers

スポンサーリンク

概要

• 論文の詳細を見る

• Pantethine and fursultiamine have been evaluated for their clinical usefulness in the treatment and prevention of uncomplicated postoperative adhesive intestinal obstruction. In recent years, the actions of drugs used to treat gastrointestinal diseases have been elucidated pharmacologically from the viewpoints of gastrointestinal peptide levels. We examined the effects of pantethine and fursultiamine on plasma levels of calcitonin gene-related peptide (CGRP)-, vasoactive intestinal polypeptide (VIP)-, motilin- and substance P (SP)-like immunoreactive substances (IS) in healthy subjects. An open-labeled study was conducted on five healthy volunteers. Each subject was administered a single oral dose of pantethine, fursultiamine and placebo at intervals of one month. Venous blood samples were collected before and at 20, 40, 60, 90, 120, 180 and 240 min after each administration. Plasma peptide levels were measured using a highly sensitive enzyme immunoassay. A single oral dose of pantethine resulted in significant increases of plasma CGRP- and VIP-IS levels compared to placebo. Furthermore, areas under the plasma concentration–time curves (AUC0—240) of CGRP- and VIP-IS were significantly higher after pantethine administration compared with placebo. On the other hand, fursultiamine had no effect on plasma levels and AUC0—240 of CGRP-, VIP-, motilin- and SP-IS. This study demonstrated the different effects of pantethine and fursultiamine from the viewpoint of plasma gastrointestinal peptide changes. The pharmacological effects of pantethine may be closely related to the changes in plasma CGRP- and VIP-IS levels.

著者

• Sasano H

  Tohoku University 21st Century Coe Program 'comprehensive Research And Education Center For Pla

• Sakamoto Hironosuke

  高崎健康福祉大学 看護学部看護学科

• Sakamoto Hironosuke

  群馬大学 医学系研究科総合診療部

• Sumino Hiroyuki

  高崎健康福祉大学 看護学部看護学科

• Sato Hiroko

  群馬大学 臓器病態内科学

• Hisamichi Shigeru

  東北大学 医学部保健学科地域保健学分野

• Seki H

  Department Of Medicine And Biological Science Graduate School Of Medical Sciences Gunma University

• Hisamichi Shigeru

  修紅短大

• Sasano Hironobu

  Department Of Pathology Tohoku University Hospital

• Hisamichi Shigeru

  Tohoku University 21st Century Coe Program 'comprehensive Research And Education Center For Pla

• Itoh Hiroki

  Department Of Cardiology Tokyo Women's Medical University

• Takeyama Masaharu

  Department Of Anesthesiology And Critical Care Medicine Kagoshima University School Of Medicine

• SUZUKI Yosuke

  Department of Applied Physics, Osaka University

• Sato Yuhki

  Department Of Clinical Pharmacy Oita University Hospital

• Abe Tomohide

  Department Of Pharmacology Kumamoto University

• Itoh Hiroki

  大分大学医学部附属病院 薬剤部

• Sakamoto Hironosuke

  The Department Of General Medicine Gunma University School Of Medicine

• Hisamichi Shigeru

  Department Of Nephrology Saitama Medical University

• Satoh Hiroshi

  Division Of Gastroenterological Surgery Department Of Surgery Tohoku University Graduate School Of M

• Nishimura Fumihiro

  Department of Clinical Pharmacy, Oita University Hospital

• Suzuki Yosuke

  Department Of Clinical Pharmacy Oita University Hospital

• Abe Tomohide

  Department Of Clinical Pharmacy Oita University Hospital

• Nishimura Fumihiro

  Department Of Clinical Pharmacy Oita University Hospital

• Sato Hiroko

  Department Of Medicine And Biological Science Graduate School Of Medical Sciences Gunma University

• Sakamoto Hironosuke

  Departments Of General Practice Medicine Gunma University Graduate School Of Medicine

• Suzuki Yosuke

  Department Of Applied Physics Osaka University

関連論文

• Radiation Dose and Radiation Protection for Patients and Physicians During Interventional Procedure
• The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension
• PE-082 Sex Differences of Coronary Plaque Component in Patients with Coronary Spastic Angina : Virtual Histology Study(PE014,Intravascular Imagings (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• The association between masked hypertension and waist circumference as an obesity-related anthropometric index for metabolic syndrome : the Ohasama study
• PE-037 A Q312X Mutation in the Hemojuvelin Gene is Associated with Cardiomyopathy due to Juvenile Hemochromatosis(Cardiomyopathy, basic/clinical(03)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OE-323 Functional Assay of von Willebrand Factor (VWF) and VWF-cleaving Protease (ADAMTS13) Activity in Acute Myocardial Infarction(Acute myocardial infarction, clinical(pathophysiology)(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeti
• PJ-704 Delays of Hospital Admission from the Onset of Acute Myocardial infarction Induce Poor Prognosis in Women in Kumamoto Prefecture(Preventive medicine/Epidemiology/Education-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Ten-Year Patency and Factors Causing Restenosis After Endovascular Treatment of Iliac Artery Lesions
• OJ-025 Ten-year Patency of Endovascular Treatment Based on the TransAtlantic Inter-Society Consensus II Classification in Patients with Iliac Artery Lesions(OJ05,Peripheral Circulation/Vascular Disease (Therapy) 1 (H),Oral Presentation (Japanese),The 73rd
• OJ-080 Long-term Results of TransAtlantic Inter-Society Consensus II(TASC-II) Stratification for Percutaneous Peripheral Intervention(PPI) in Patients with Peripheral Arterial Disease(PAD).(Peripheral circulation/Vascular disease(02)(H),Oral Presentation(
• Aldosterone, but Not Angiotensin II, Reduces Angiotensin Converting Enzyme 2 Gene Expression Levels in Cultured Neonatal Rat Cardiomyocytes
• PJ-321 Clinical Factors Affecting Serum Potassium Concentration(Heart failure, clinical(16)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OE-295 Coronary Microvessel Spasm is a Frequent Cause of Myocardial Ischemia in Postmenopausal Women with Angina-like Chest Pain(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd Annual Scientif
• FRS-066 When and How should We Use Central BP in Clinical Hypertension? : Report from ABC-J Study(FRS14,New Aspects for Hypertension (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-145 Multi-center Cross-sectional Study to Characterize Antihypertensive Treatments in terms of Central Blood Pressure Evaluated by Radial Artery Pulse Waveform(Hypertension, clinical(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting
• PJ-790 Effects of Adding Eplerenone to Standard Therapy on Sympathetic Nerve Activity and Myocardial Collagen Metabolism in Congestive Heart Failure Patients(PJ133,Heart Failure (Treatment) 4 (M),Poster Session (Japanese),The 73rd Annual Scientific Meetin
• PJ-668 Relationship between Endogenous Free Testosterone Levels and Degree of Coronary Artery Atherosclerosis in Men(PJ112,Atherosclerosis (Clinical/Pathophysiology) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circ
• PJ-663 Usefulness of Serial ^TI/^I-BMIPP Dual SPECT in Predicting Functional Recovery after Coronary Artery Bypass Grafting in Coronary Artery Disease Patients(PJ111,Angina Pectoris (Clinical) (IHD),Poster Session (Japanese),The 73rd Annual Scie
• PJ-530 Post Procedural Creatinine Increase is Associated with Endothelial Dysfunction in Patients with Early Stage of Chronic Kidney Disease(PJ089,Atherosclerosis (Clinical/Pathophysiology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meet
• PJ-510 Evaluation of Sympathetic Nerve Activity in Patients with Decompensated Acute Heart Failure on the Treatment Containing Intravenous Atrial Natriuretic Peptide(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientifi
• PJ-509 Serial ^I-Metaiodobenzylguanidine Scintigraphic Studies are More Useful for Predicting Cardiac Death than One-time Scan in Patients with Chronic Heart Failure(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scie
• PJ-361 Long-term Intravenous Atrial Natriuretic Peptide Therapy Improves Sympathetic Nerve Activity than Short-term Therapy in Patients with Decompensated Acute Heart Failure(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Japanese),
• PJ-360 Effects of Immediate Administration of Mineralocorticoid Receptor Antagonist Spironolactone on Cardiac Sympathetic Nerve Activity in Patients with Acute Myocardial Infarction(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Jap
• PJ-328 Relationship between Heart Diseases Evaluated by Echocardiogram and Survival Rates in Patients with Peripheral Arterial Disease(PJ055,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 2 (H),Poster Session (Japanese),The 73rd Annual S
• PJ-326 Chronic Kidney Disease and Insulin Resistance are Risk Factors of Calcified Plaque-Morphology in Patients with Peripheral Arterial Disease(PJ055,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 2 (H),Poster Session (Japanese),The 73
• PJ-243 Activation of Endocannabinoid System in Patients with Coronary Artery Disease and Cardiometabolic Risk Factors(PJ041,Atherosclerosis (Clinical/Pathophysiology/Treatment/Diagnosis) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting o
• PJ-241 Cannabinoid 1 Receptor Blockade with Rimonabant Reduces Atherosclerosis thorough Elevation of Adiponectin and Activation of Reverse Cholesterol Transport System(PJ041,Atherosclerosis (Clinical/Pathophysiology/Treatment/Diagnosis) (IHD),Poster Sessi
• PJ-220 Adding Eplerenone to Standard Therapy Improves Sympathetic Nerve Activity and Prevents Left Ventricular Remodeling in Patients with Congestive Heart Failure(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd An
• PJ-219 Effects of Statin on Sympathetic Nerve Activity and Incidence of Major Adverse Cardiac Events in Patients with Acute Myocardial Infarction(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Me
• PJ-176 Hypercholesterolemia and Hypoadiponectinemia are Risk Factors for Coronary Plaque Vulnerability(PJ030,Metabolic Syndrome 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-118 Runx2 Represses TGF β/Smad-mediated Connective Tissue Growth Factor Gene Expression in Vascular Smooth Muscle Cells(PJ020,Atherosclerosis, Basic 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Societ
• PJ-052 Quantitative Assessment of Total Coronary Artery Plaques Volume Using Multi-slice Computed Tomography is Associated with Metabolic Syndrome(PJ009,CT/MRI (Coronary/Vascular) 4 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The J
• PE-499 Cholesterol Absorption and Synthesis in Type-2 Diabetic Patients Requiring Cholesterol Lowering Therapy(PE084,Lipid Disorders 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-269 Digital Assessment of Endothelial Function and Ischemic Heart Disease in Women(PE045,ACS/AMI (Clinical/Treatment) 2 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Von Willebrand Factor-cleaving Protease (ADAMTS-13), a Novel Marker for Coronary Thrombosis in Acute Coronary Syndrome(Acute Coronary Syndrome, Basic/Clinical 4 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Intrathoracic Giant Meningocele Associated with Neurofibromatosis
• Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity in women--Aging, HRT, and skin elasticity
• PJ-228 Osteogenic Transcription Factor Runx2 represses Connective Tissue Growth Factor Gene Expression and TGFbeta Signaling in Vascular Smooth Muscle Cells(Atherosclerosis, basic(06)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the
• PJ-729 Elevated Arterial Stiffness in Postmenopausal Women with Osteoporosis(Atherosclerosis, clinical-15 (H) PJ123,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Effect of Cerivastatin on Endothelial Dysfunction and Aortic CD36 Expression in Diabetic Hyperlipidemic Rats
• Vascular Endothelial Growth Factor is an Autocrine Growth Factor for Cardiac Myxoma Cells
• PE-460 Effect of Statin Therapy on Endothelial Dysfunction and Aortic CD36 Expression in Diabetic Hyperlipidemic Rats(Diabetes/Obesity 4 (H) : PE78)(Poster Session (English))
• PE-231 FGF-2 Changes Vascular Smooth Muscle Cell Fate and Induce Osteoblastic Marker Gene Expression via cbfa1.(Vascular Smooth Muscle 1 (H) : PE40)(Poster Session (English))
• PE-043 Klotho transgenic rats show a decrease in oxidative stress and result in restoration in endothelial function(Endothelium/NO 1 (H) : PE8)(Poster Session (English))
• FRS-157 Klotho-defecient mice show endothelial dysfunction and salt-sensitive hypertension(Hypertension (H) : FRS19)(Featured Research Session (English))
• Crosstalk between c-Src- and Smad-Dependent Pathways Regulates the TGF-β-Induced SMC-Specific Gene Expression in Murine Embryonic Fibroblast 10T1/2 Cells
• bFGF Inhibits the TGFβ-Induced SM22α Gene Expression by CBFA1 through MAP Kinase Pathways in Embryonic Fibroblast Cells
• Proposal of a Risk-Stratification System for the Japanese Population Based on Blood Pressure Levels : The Ohasama Study
• Reproducibility of Nocturnal Blood Pressure Assessed by Self-Measurement of Blood Pressure at Home
• Increase of Colon and Rectal Cancer Incidence Rates in Japan: Trends in Incidence Rates in Miyagi Prefecture, 1959-1997
• Reliability and Validity of the Multidimensional Health Locus of Control Scale in Japan : Relationship with Demographic Factors and Health-Related Behavior
• Health Practices and Mortality in Japan : Combined Effects of Smoking, Drinking, Walking and Body Mass Index in the Miyagi Cohort Study
• Body Mass Index and Mortality in Japan : The Miyagi Cohort Study
• Walking and Mortality in Japan : The Miyagi Cohort Study
• Pueraria Mirifica Phytoestrogens Improve Dyslipidemia in Postmenopausal Women Probably by Activating Estrogen Receptor Subtypes
• PJ-436 Impaired Vascular Endothelial Function in Postmenopausal Women with Osteoporosis(Atherosclerosis, clinical-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-435 Raloxifene is Effective for Reducing Carotid Artery Wall Thickness and Increasing Bone Mineral Density in Postmenopausal Women with Osteoporosis(Atherosclerosis, clinical-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Production of Endothelin-1 and Big Endothelin-1 by Human Cardiac Myxoma Cells : Implications for the Origin of Myxomas
• Effects of Hormone Replacement Therapy on Office and Ambulatory Blood Pressure in Japanese Hypertensive Postmenopausal Women
• Effects of Hormone Replacement Therapy on Circulating Docosahexaenoic Acid and Eicosapentaenoic Acid Levels in Postmenopausal Women
• Effects of Hormone Replacement Therapy on Serum Angiotensin-Converting Enzyme Activity and Plasma Bradykinin in Postmenopausal Women According to Angiotensin-Converting Enzyme-Genotype
• Practical assessment of myocardial viability with a positron coincidence gamma camera using ^F-fluorodeoxyglucose in acute myocardial infarction : Comparison with dedicated positron emission tomography and ^Tl single photon emission computed tomo
• PJ-790 Effects of Adding Eplerenone to Standard Therapy on Sympathetic Nerve Activity and Myocardial Collagen Metabolism in Congestive Heart Failure Patients(PJ133,Heart Failure (Treatment) 4 (M),Poster Session (Japanese),The 73rd Annual Scientific Meetin
• PJ-663 Usefulness of Serial ^TI/^I-BMIPP Dual SPECT in Predicting Functional Recovery after Coronary Artery Bypass Grafting in Coronary Artery Disease Patients(PJ111,Angina Pectoris (Clinical) (IHD),Poster Session (Japanese),The 73rd Annual Scie
• PJ-589 Effect of Cardiac Rehabilitation Program on Renal Function in Patients with Cardiovascular Disease(PJ099,Exercise Test/Cardiac Rehabilitation 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-510 Evaluation of Sympathetic Nerve Activity in Patients with Decompensated Acute Heart Failure on the Treatment Containing Intravenous Atrial Natriuretic Peptide(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientifi
• PJ-509 Serial ^I-Metaiodobenzylguanidine Scintigraphic Studies are More Useful for Predicting Cardiac Death than One-time Scan in Patients with Chronic Heart Failure(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scie
• PJ-361 Long-term Intravenous Atrial Natriuretic Peptide Therapy Improves Sympathetic Nerve Activity than Short-term Therapy in Patients with Decompensated Acute Heart Failure(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Japanese),
• PJ-360 Effects of Immediate Administration of Mineralocorticoid Receptor Antagonist Spironolactone on Cardiac Sympathetic Nerve Activity in Patients with Acute Myocardial Infarction(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Jap
• PJ-220 Adding Eplerenone to Standard Therapy Improves Sympathetic Nerve Activity and Prevents Left Ventricular Remodeling in Patients with Congestive Heart Failure(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd An
• PJ-219 Effects of Statin on Sympathetic Nerve Activity and Incidence of Major Adverse Cardiac Events in Patients with Acute Myocardial Infarction(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Me
• PE-506 Comprehensive Cardiac Rehabilitation Program Strongly Prevents New Onset of Myocardial Ischemia in Patients Received Percutaneous Coronary Intervention(PE085,Exercise Test/Cardiac Rehabilitation (H),Poster Session (English),The 73rd Annual Scientif
• PE-310 Influence of Chronic Kidney Diseases on the Diastolic Left Ventricular Function(PE052,Kidney/Renal Circulation/CKD 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PE-126 Follow-up Data of hANP/Nicorandil Combined Therapy in AMI Shows Usefulness to Salvage Myocardium, Improve Cardiac Function, Suppress Left Ventricular Remodeling(PE021,ACS/AMI (Clinical/Treatment) 1 (IHD),Poster Session (English),The 73rd Annual Sci
• PE-115 Beneficial Usage of Metabolic Syndrome for Screening of Cardiovascular Disease with Myocardial Scintigraphy(PE020,Nuclear Cardiology (Coronary, Myocardium) (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation
• PE-027 In Early Stage of Metabolic-Syndrome, Male Waist-Circumference and Female HDL-Cholesterol are Most Important Factors for Cardiovascular Disease on Myocardial Scintigraphy(PE005,Metabolic Syndrome 1 (H),Poster Session (English),The 73rd Annual Scien
• OJ-254 Prognostic Value of Cardiac Sympathetic Nerve Activity Evaluated by ^I-Metaiodobenzylguanidine Imaging in Patients with Acute Myocardial Infarction(OJ43,Nuclear Cardiology (Coronary, Myocardium) (I),Oral Presentation (Japanese),The 73rd Annual
• OJ-183 Long-term Nicorandil Therapy Improves Cardiac Sympathetic Nerve Activity after Reperfusion Therapy in Patients with First Acute Myocardial Infarction(OJ31,ACS/AMI (Clinical/Treatment) (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Me
• PJ-790 Effects of Adding Eplerenone to Standard Therapy on Sympathetic Nerve Activity and Myocardial Collagen Metabolism in Congestive Heart Failure Patients(PJ133,Heart Failure (Treatment) 4 (M),Poster Session (Japanese),The 73rd Annual Scientific Meetin
• PJ-668 Relationship between Endogenous Free Testosterone Levels and Degree of Coronary Artery Atherosclerosis in Men(PJ112,Atherosclerosis (Clinical/Pathophysiology) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circ
• PJ-663 Usefulness of Serial ^TI/^I-BMIPP Dual SPECT in Predicting Functional Recovery after Coronary Artery Bypass Grafting in Coronary Artery Disease Patients(PJ111,Angina Pectoris (Clinical) (IHD),Poster Session (Japanese),The 73rd Annual Scie
• PJ-530 Post Procedural Creatinine Increase is Associated with Endothelial Dysfunction in Patients with Early Stage of Chronic Kidney Disease(PJ089,Atherosclerosis (Clinical/Pathophysiology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meet
• PJ-510 Evaluation of Sympathetic Nerve Activity in Patients with Decompensated Acute Heart Failure on the Treatment Containing Intravenous Atrial Natriuretic Peptide(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientifi
• PJ-509 Serial ^I-Metaiodobenzylguanidine Scintigraphic Studies are More Useful for Predicting Cardiac Death than One-time Scan in Patients with Chronic Heart Failure(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scie
• PJ-361 Long-term Intravenous Atrial Natriuretic Peptide Therapy Improves Sympathetic Nerve Activity than Short-term Therapy in Patients with Decompensated Acute Heart Failure(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Japanese),
• PJ-360 Effects of Immediate Administration of Mineralocorticoid Receptor Antagonist Spironolactone on Cardiac Sympathetic Nerve Activity in Patients with Acute Myocardial Infarction(PJ061,Nuclear Cardiology (Coronary, Myocardium) 2 (I),Poster Session (Jap
• PJ-328 Relationship between Heart Diseases Evaluated by Echocardiogram and Survival Rates in Patients with Peripheral Arterial Disease(PJ055,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 2 (H),Poster Session (Japanese),The 73rd Annual S
• PJ-326 Chronic Kidney Disease and Insulin Resistance are Risk Factors of Calcified Plaque-Morphology in Patients with Peripheral Arterial Disease(PJ055,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 2 (H),Poster Session (Japanese),The 73
• PJ-243 Activation of Endocannabinoid System in Patients with Coronary Artery Disease and Cardiometabolic Risk Factors(PJ041,Atherosclerosis (Clinical/Pathophysiology/Treatment/Diagnosis) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting o
• PJ-241 Cannabinoid 1 Receptor Blockade with Rimonabant Reduces Atherosclerosis thorough Elevation of Adiponectin and Activation of Reverse Cholesterol Transport System(PJ041,Atherosclerosis (Clinical/Pathophysiology/Treatment/Diagnosis) (IHD),Poster Sessi
• PJ-220 Adding Eplerenone to Standard Therapy Improves Sympathetic Nerve Activity and Prevents Left Ventricular Remodeling in Patients with Congestive Heart Failure(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd An
• PJ-219 Effects of Statin on Sympathetic Nerve Activity and Incidence of Major Adverse Cardiac Events in Patients with Acute Myocardial Infarction(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Me
• PJ-118 Runx2 Represses TGF β/Smad-mediated Connective Tissue Growth Factor Gene Expression in Vascular Smooth Muscle Cells(PJ020,Atherosclerosis, Basic 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Societ
• PJ-052 Quantitative Assessment of Total Coronary Artery Plaques Volume Using Multi-slice Computed Tomography is Associated with Metabolic Syndrome(PJ009,CT/MRI (Coronary/Vascular) 4 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The J
• Renoprotective Effect of Losartan in Comparison to Amlodipine in Patients with Chronic Kidney Disease and Hypertension-a Report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) Study
• Evaluation of myocardial viability following acute myocardial infarction using ^Tl SPECT after thallium-glucose-insulin infusion : Comparison with ^F-FDG positron emission tomography
• Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma
• OE-001 Impact of Cytochrome P450 2C19 Polymorphism on Platelet Function after Treatment with Clopidogrel in Japanese Patients of Coronary Artery Disease(OE01,Cardiovascular Pharmacology (Clinical) (H),Oral Presentation (English),The 73rd Annual Scientific
• 2 Long-term Clinical Outcome after Intramuscular Implantation of Bone Marrow Mononuclear Cells (TACT Trial) in Patients with Chronic Limb Ischemia(Regenerative Therapy for Peripheral Artery Disease,Symposium 12 (SY-12) (I),The 73rd Annual Scientific Meeti
• High Ratio of Myeloid Dendritic Cells to Plasmacytoid Dendritic Cells in Blood of Patients With Acute Coronary Syndrome

もっと見る 閉じる

スポンサーリンク