A case of trichilemmal carcinoma after kidney transplantation.

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A 41-year-old man, who had received a kidney transplant in the U.S.A. because of chronic renal failure and been controlled with immunosuppresion therapy (azathioprine and cyclosporine) for about 4 years, developed an elastic-hard node(1cm in diameter) on the lower abdominal wall.Histopathologically, an excisional biopsy of the tumor revealed that there was invasive growth of epithelial cells into the upper dermis. The peripheral cell layer of the tumor masses showed basophilic, palisading, and the centrally located cells showed atypical nuclei amd a pa1e-stainimg cytoplasm which contained glycogen. A trichilemmal keratinization was observed. From these findings a trichilemmal carcinoma was made, and subsequently an extensive resection was performed. The incidence of malignant tumors following kidney transplantation is high. The graft survival rate is being improved, and thus the management of the malignant tumorsfollowing kidney transplantation is considered to be an important issue.