Plasma somatomedin C/insulinlike growth factor I in the liver diseases.

概要

論文の詳細を見る
Plasma somatomedin C/insulinlike growth factor I (Sm-C/IGF I) was estimated by radioimmunoassay in 9 patients with chronic hepatitis, 17 with liver cirrhosis, 3 with acute hepatitis and 7 control subjects.In the patients with chronic liver diseases a negative correlation was found between plasma Sm-C/IGF I levels and ICG R15 values, and then there was a positive correlation between plasma Sm-C/IGF I levels and serum ChE activity, albumin and HPT values.In the patients with acute hepatitis plasma Sm-C/IGF I levels decreased during acute illness and returned to normal with recovery. No correlation was found between plasma Sm-C/IGF I levels and serum GH values in the patients either chronic liver diseases or acute hepatitis.These findings suggest that plasma Sm-C/IGF I levels are reduced in proportion to the degree of hepatic damage and that they are not dependent on serum GH values.
財団法人日本消化器病学会の論文