胃過形成性ポリープの癌化について

概要

論文の詳細を見る
Hyperplastic polyps, removed by endoscopic polypectomy, were reviewed with special reference to appearance of dysplastic focus and its malignant transformation.Hyperplastic polyps were seen in 477 lesions corresponding to 89.7% of the total 532 lesions removed by endoscopic polypectomy. Focal carcinoma were found in 10 hyperplastic polyps, which corresponded to 2.1% of the total 477 hyperplastic polyps. Dysplastic foci equivalent in the degree of histologic atypia to adenoma or "atypical epithelium" were found adjacent to the cancerous focus in these 10 polyps.Dysplastic foci were also found in 19 hyperplastic polyps without cancerous focus, which corresponded to 4.0% of the total hyperplastic polyps.The results of the clinicopathological study of these hyperplastic polyps with dysplastic foci and carcinoma suggested that cancer cells arose from the dysplastic area in hyperplastic polyps rather than directly from non-dysplastic hyperplastic epithelium.
財団法人日本消化器病学会の論文