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In order to compare radiological finding of the dilated branches on post-mortem pancreatogram with the histological findings, of 20 necropsy materials were studied (30 dilated branches).In the simple dilatation group (5 branches), goblet cell hyperplasia, disruption and disappearance of elastic fibers were seen in the dilated ducts. Acinar cell atrophy and disappearance, fibrosis and ductular aggregation were mild in drainage lobules. This group may be associated with several diseases, including chronic pancreatitis.In the irregular dilatation group (14 branches), inflammatory cell infiltration, periductal fibrosis and fat replacement were seen in addition to the above histological findings. These findings were moderate to severe in drainage lobules. This group is compatible with chronic pancreatitis.In the cystic dilated group (11 branches), plug like substances were seen in addition to the above findings. This group is also related to chronic pancreatitis.It is concluded that irregular dilatation and cystic dilatation of branches would be significant in ERCP diagnosis of chronic pancreatitis.
- 財団法人 日本消化器病学会の論文