Non-erythropoietic Component of Early Labelled Bilirubin in Patients with Cirrhosis and Acute Hepatitis (Recovery Stage)

概要

論文の詳細を見る
Non-erythropoietic component of early labelled bilirubin was studied in 7 acute infectious hepatitis patients (in recovery stage), 18 cirrhotic patients and in 7 control subjects with plasma and bile, after injection of 2.5μc of [4-14C] δ-aminolaevulinic acid intravenouslly. All cases were examined in the nonicteric stage (total serum bilirubin below 1.5mg/dl). The mean cumulative radioactivities in 4 hours in the control subjects were 29.6±4.7×103 D.P.M./mg x hrs. in plasma, and 27.0±1.2×103D.P.M./mg x hrs. in bile.In acute hepatitis patients (in recovery stage), the mean cumulative radioactivities in 4 hours in both plasma and bile were approximately twice as large as that in control subjects. (P<0.001 and <0.005 respectively). In cirrhotic patients with large sized liver scintigrams, the mean cumulative radioactivities in both plasma and bile were approximately 1.4 times as large as that in control subjects. (P<0.001 both in plasma and bile).In cirrhotic patients with medium sized liver scintigrams, the mean cumulative radioactivities in both plasma and bile were approximately the same as large as that in control subjects.In cirrhotic patients with markedly small sized liver scintigrams, the mean cumulative radioactivities in both plasma and bile were approximately one half as large as that in cotrol subjects. (P<0.001 both in plasma and bile).In the cirrhotic patients, two peaks of bilirubin activities were observed in many cases in both plasma and bile. The more the cirrhosis advanced with the liver reduced in size, the more the cases showed two peaks.
財団法人日本消化器病学会の論文

Non-erythropoietic Component of Early Labelled Bilirubin in Patients with Cirrhosis and Acute Hepatitis (Recovery Stage)

スポンサーリンク

概要

著者

関連論文

スポンサーリンク