PLASMA GASTRIN RESPONSE TO TEST MEAL AND GASTRIC ACID SECRETION GASTRIC EMPTYING:[II] Comparative Study among the Benign Gastroduodenal Diseases
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A comparative study about plasma gastrin response to test meal was performed in contrast to gastric acid secretion and gastric emptying among the patients with gastric ulcer, duodenal ulcer, erosive gastritis, atrophic gastritis and normal subjects.The patients with erosive gastritis and atrophic gastritis showed significantly higher integrated increments in plasma gastrin responses than normal subjects. The patients with duodenal ulcer and gastric ulcer showed rather low integrated increments in plasma gastrin responses although statistically significant differences were not observed as compared with normal subjects. But the value of standard deviation was considerably large in each disease. It was considered that this fact suggested the complexity of the physiologic condition of each disease and the patients had to be divided into some groups by various items in each disease. The patients with atrophic gastritis was divided into two groups by fasting gastrin levels: the patients whose fasting gastrin levels were more than 150pg/ml showed significantly higher plasma gastrin responses to the meal than the patients whose fasting gastrin levels were less than 150pg/ml. The patients with duodenal ulcer who had erosive gastritis showed significantly higher responses than those who had not erosive gastritis.No particular correlation was observed on the whole between plasma gastrin response to the meal and gastric acid secretion or gastric emptying.
- 財団法人 日本消化器病学会の論文
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