アルテミアにおけるブラシカステロールからコレステロールへの変換

概要

論文の詳細を見る
In the present study, the bioconversion of the dietary brassicasterol in Artemia salina was investigated. After administration of the Cyclotella nana containing brassicasterol-14C to Artemia, the sterols were isolated from the tissues of Artemia. The isolated sterol was found to contain only cholesterol and to reveal relatively high radioactivity. In column chromatography on a silver nitrate-impregnated silicic acid as acetate, cholesterol-14C gave one radioactive peak corresponding to cholesteryl acetate. Moreover, cholesteryl acetate-14C showed a constant specific activity (dpm/mg) during repeated crystallizations. On the basis of these results, it was concluded that Artemia is capable of converting the dietary brassicasterol to cholesterol.