Plasma .BETA.-phenylethylamine in Parkinson's Disease.

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概要

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• Plasma β-phenylethylamine (PEA) levels were determined in 27 patients with Parkinson's disease (PD) in order to evaluate its relation with the severity or clinical course of PD. The plasma PEA concentrations in PD patients were significantly lower (mean±SD, 862±554 pg/ml) than those in the control group (1765±790 pg/ml) (p <0.0001). The concentrations of PEA in plasma did not correlate with Hoen and Yahr stage. However, in serial measurements of the PEA of 5 patients in the progressive group of the clinical course of PD, the plasma PEA levels revealed a downward trend after one or two years. On the other hand, in 3 patients of non-progressive group, the plasma PEA remained at the same level. This study suggests that plasma PEA level might reflect nigrostriatal degeneration in patients with PD.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• MIURA Yumiko

  Department of Applied Chemistry, Shibaura Institute of Technology

• MIURA YUMIKO

  Department of Medicine, Kurume University School of Medicine

関連論文

• An Electrolytic System Based on the Acid-Base Reaction between Solid-Supported Acids and Water
• Plasma .BETA.-phenylethylamine in Parkinson's Disease.

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