鉤虫症の病態生理に関する研究

概要

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We examined 472 patients of the hookworm disease who consulted our clinic in 1951-'55 and 54 patients in 1946-'48 comparing with symptoms after the World War. After World War II, subjective symptoms which were caused by unwell nourishment, for example tiredness, fatigue and emaciation, were recognized at the high percentage. Slightly fever (above 37°C) were seen in 31.7%. Many cases complained pain upon the pressure on 3cm right lower part of navel. The liver enlargement were seen in 32.6% and the urobilinogen reaction of the urine were positive in 23.3%. Some patients revealed positive liver function test, especially C. C. F. were found sensitively. Many cases showed hypochromic microcytic anemia and each values and indexes were paralled with the degree of the anemia. Many cases showed eosinophilia in blood and the number of eosinophylic leucocytes related to the degree of the anemia. When the grade of anemia were severe, the eosinophylic leucocyte increased. But in some cases of severe anemia missed the eosinophylic leucocyte. Plasma protein decreased in many cases of the patients. We recognized various symptoms, anemia, enlargement of the liver and disturbance of liver function in 63 cases of hookworm carrier. Considering the above finding, it seems necessary to treat the carriers of hookworm as the patient of hookworm disease.
社団法人日本内科学会の論文