TRAUMATIC EFFECTS ON SPONTANEOUS EEG AND EVOKED RESPONSE IN FLUID-PERCUSSION MODEL OF HEAD INJURY
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概要
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We tried to determine the localization of reversible impairment of brain function in a percussion model of head injury. In our experiments, 30 cats were immobilized and artificially ventilated. Traumatic impact was adminis-tered by a sudden input of water into the epidural space at the right parietal region. Using EEG, SER, VER, and ECG as indexes of brain function, we evaluated traumatic effect. Intensity of impact showed closer correlation with change of SER than with change of EEG or VER. Impact first caused re-duction and flattening of polysynaptic components of SER. When impact was intensified, all components of SER were flattened and EEG was desyn-chronized. Immediate post-impact VER had a simple form, but soon returned to pre-impact form. From these indexes, we estimated that in this percussion model, the function of the lower brain stem was most vulnerable to impact. In about half of cases, suppression of lower brain stem function transiently reappeared at 10-15 minutes into recovery. When impact was much more intensified, SER remained flat throughout observation. EEG and VER re-covered fairly even in cases with continuously flat SER.
- The Keio Journal of Medicineの論文
著者
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Tsukumo Daizo
Division Of Neurological Surgery:departmenet Of Surgery Keio University School Of Medicine
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TSUKUMO DAIZO
Division of Neurosurgery, The Seishin-Igaku Institute
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- TRAUMATIC EFFECTS ON SPONTANEOUS EEG AND EVOKED RESPONSE IN FLUID-PERCUSSION MODEL OF HEAD INJURY