気液固3相ハニカムモノリスバイオリアクタ-の特性--固定化グルコ-スオキシダ-ゼによるグルコ-スの酸化

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The gas-liquid and liquid-solid mass transfer rates in a honeycomb monolithic bioreactor were measured, and the performance of this bioreactor was tested using oxidation of glucose by immobilized glucose oxidase. At the low liquid flow rates adopted in the experiments, two-phase flow in the monolith channels is in slug flow regime for cocurrent upflow, and is in liquid annular flow regime for cocurrent downflow. The upflow operation gave three to five times higher rates for both gas-liquid and liquid-solid mass transfer than did the downflow operation.<BR>The conversion of glucose by immobilized glucose oxidase was also two to three times higher with upflow than with downflow. It was confirmed by model calculation that the liquid-solid mass transfer of oxygen was controlling in the downflow operation, and higher conversion in the upflow operation was due to the reduction of this resistance.
社団法人化学工学会の論文