メニエール病の保存的治療に対する検討一イソソルビドの使用経験-

概要

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The therapeutic effect of Isosorbide was evaluated in 43 patients (20 males and 23 females) with Meniere's disease. Vertigo was reduced in 24 patients (87%) after 8 weeks of treatment. However, in some patients vertigo became worse and nystagumus was observed again. A follow-up study of 24 patients treated for 2 or more years was analyzed by AAOO and A AO-HNS evaluation criteria. According to the AAOO criteria, definite attacks were reduced in 9 patients (69%) who were under medication for more than 6 months, and 10 patients (91%) who were under medication for 6 months or less. According to the AAO-HNS criteria, definite attacks were reduced in 10 patients (77%) who were under medication for more than 6 months, and in 10 patients (91%) who were under medication for 6 months or less. In the follow-up study, hearing was not improved, but tinnitus was reduced in 9 patients (38%). While under medication, definite attacks still occurred in some patients. In conclusion, further research is needed to determine the dosage of Isosorbide required for the treatment of Meniere's disease.
一般社団法人日本めまい平衡医学会の論文