A clinical study of Meniere's disease. With special reference to bilateral aspects.:With Special Reference to Bilateral Aspects
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概要
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The course of Meniere's disease was followed in 195 patients (137 with unilateral disease and 58 with bilateral fluctuating hearing loss).<BR>(1) In unilateral cases, hearing levels fell in 3 years to an average of 30 dB, followed by annual increases of 10 dB for the next 10 years. Deterioration then usually ceased. In the first involved ear in bilateral cases, hearing levels increased during the first year to an average of 50 dB, followed by a total 20 dB increase over the next 10 years. After this time another rapid deterioration occurred. Second involved ears showed hearing level increases averaging a total of 20 dB over the first 4 years, after which hearing rapidly deteriorated to the level of the first involved ear by the 10th year.<BR>(2) Vertigo attacks were most frequent during the first year, then decreased rapidly the second year, followed by more gradual decreases. Unilateral and bilateral cases showed an almost equal incidence of attacks.<BR>(3) In unilateral cases, caloric responses of the affected ears decreased steadily to approximately 60% of those of unaffected ears by the end of the second decade. Caloric responses in bilateral cases fell to approximately 50% of normal levels. The rate of reduction in both 1st and 2nd ears was almost the same.<BR>(4) The general course of bilateral cases differed from that of unilateral cases, suggesting the possibility of different etiologies and/or pathophysiologies. Accurate early diagnosis is thus of great importance. During our long term study it was found that : <BR>(5) Most suspected cases receiving definitive diagnoses showed recurrent vertigo attacks and cochlear symptoms such as hearing difficulty and/or tinnitus at the time of the first examination, though fluctuation was not evident.<BR>(6) Positive glycerol tests were generally predictive of later definite Meniere's disease.<BR>(7) Repetitive audiometry was useful for the confirmation of definite disease.
- 一般社団法人 日本めまい平衡医学会の論文
一般社団法人 日本めまい平衡医学会 | 論文
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