Wallenberg's syndrome caused by brain tumor. A case report and review of the literature.

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In the majority of cases Wallenberg's syndrome is due to infarction in the are supplied by the posterior inferior cerebellar artery, but rarely other causes can also produce it. We describe a patient with the syndrome caused by glioma of the lateral medulla oblongata, and review the literature of Wallenberg's syndrome associated with neoplastic disease.<BR>A 46-year-old man admitted because of progressive dysphagia and vertigo. Neurological examination revealed atypical symptoms and signs of Wallenberg's syndrome on the right side ; hypalgesia of the second and third divisions of the left trigeminal verve, paresis of the right palate and uvula, and ataxia of the right extremities. Although CT showed no abnormality in the posterior fossa, MRI demonstrated a mass with abnormal signal intensities in the right dorsolateral portion of the medulla. Biopsy specimens showed astrocytoma (grade III).<BR>From the present case and a review of 10 previously reported cases of Wallenberg's syndrome caused by neoplastic diseases, clinical features are characterized by gradual development and steady progression of symptoms, non-classical or atypical symptomatology, numerous additional symptoms and signs depending on the site and size of the tumor, and a poor prognosis.
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