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The action potential was recorded from an isolated frog utricle using a suction electrode. The utricle was stimulated by iron sand which was placed homogeneously on the macula. A magnetic force was employed to allow iron sand to mildly depress the macula. Integration of the action potential resulted in a phasic component just as observed in the isolated semicircular canal potential (Harada et al., 1969).<BR>The amplitude of the utricular phasic component was linear to the logarithm of the stimulus intensity. A similar relationship was observed between the semicircular canal action potential and the stimulus (Harada and Hirata, 1979).<BR>A phasic on-response was invariably accompanied by an off-response.<BR>This suggests functional polarization of the utricle. It is already known that the macula is divided by a striola into two hair cell groups with different polarities. Since iron sand is homogeneously placed on the macula, all the sensory cilia bend in one direction at the onset of the stimulus and one of the two cell groups evokes an on-response.<BR>At termination of the stimulus, sensory cells with the opposite polarity are stimulated, thus producing an off-response.
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一般社団法人 日本めまい平衡医学会 | 論文
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