副鼻腔炎における上顎洞粘膜及び骨組織に関する実験的研究

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There has been two opposite opinions about the findings of bone tissue in chronic paranasal sinusitis. Some authors consider the histological finding of the bony wall of the paranasal sinuses as pathological chronic inflammatony reaction, but the others consider it physiological. Using rabbits. tion by the following procedures, such as: various foreign bodies i.e. fragments of bone, tooth or gauze inserted into the right maxillary sinus (group 1), 2% solution of egg white albumin poured into the right maxillary sinus of the sensitized animals (group 2). The left maxillary sinuses were served as control. The results were as follows: Group 1 : In all specimens the mucous membrane of paranasal sinus showed the infiltration of inflammatory cells or the fibrosis. In the early stage, osteoclastic and ostesblastic activities were seen. In the late stage, osteoblastic activity was prominent. Group 2: The progress of the tissue rection was very rapid. The mucous membrane showed marked edema but no significant changes were observed in bone tissue in anystage.At least in chronic paranasal sinusitis with infiltrating or fibrotic type of mucosal changes, changes in the bone tissue were thought to be pathological caused by the inflammation of the mucous membrane.
社団法人日本耳鼻咽喉科学会の論文