家族性内耳性難聴の遺伝学的研究

概要

論文の詳細を見る
The causes of hearing loss in 2738 patients in Shizuoka Prefecture have been analysed since 1951 and 40 patients who belonged to familiar inner ear deafness were found. The author inves- tigated their families by means of the historical, statistical(method of Kishimoto-Kobayashi etc.) and hiometry examinations(method of Weinberg and Apelt-Bernstein etc.).The results were as follows: 1)According to the pedigrees, the possibility of heredity or rather the direct heredity was recognized. 2)The morbidity was 73.67±2.63%among 14 patients in 5 families, whose both parents had a familiar inner ear deafness. 3)The morbidity was 46, 77±3.24among 116patients in 35 families, one of whose parents had a familiar inner ear deafness. From the above stated results the author concluded that the heredity of familiar inner ear deafness was dominant and followed the Mendel's law.
一般社団法人日本耳鼻咽喉科学会の論文