オゾン曝露の家兎扁桃に及ぼす影響について : 特に走査型電子顕微鏡による扁桃表面の観察
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概要
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The effects of ozone, main constituent of oxidant, on rabbits tonsil were observed and the scanning electron-microscopic findings were compared to the microscopic findings. The results are as follows.(1) Exposure to the highly concentrated ozone (5ppm) In the microscopic observation there were remarkable stimulative changes such as detachment and falling of the tonsilar epitherium in and around the intra-surface of the lacunar layer. A large number of lacunar plugs of the tonsil was also seen. In the scanning electron-microscopic findings of the free surface of the tonsil in the oral cavity, the epitherium of the tonsilar surface was detached and fallen, and many granular globules of all sizes were distributed under the epitherial cells.(2) Exposure to the moderately concentrated ozone (1ppm) In the microscopic findings, detachment of the tonsilar epitherium and of the epitherium around the lacunar layer and cell infiltration in the lacunar epitherium were remarkably observed. There was emigration of a large number of cells. In the scanning electron-microscope findings, many granular globules were widely noticed under the epitherium which detached more slightly than in the cases of 5ppm ozone exposure.(3) Exposure to the low concentrated ozone (0.2ppm) In the microscope findings, no remarkable changes were observed in the rabbits with a shortterm exposure. But as the duration of exposure was increased detachment and disarrangement of the tonsilar epitherium and in the epitherium at the entrance of the lacunae were increased. There also noted slight cell infiltration in the intra-surface layer of the lacunae. In the scanning electron-microscope findings with a high magnification, disarrangement, falling and defect of pavement of the epitherium were observed in the free surface of the tonsil against the oral cavity and around the lacunar layer.
- 社団法人 日本耳鼻咽喉科学会の論文