耳下腺腫瘍RIシンチグラフィーの診断的意義に関する研究

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99mTcO4- and 67Ga-citrate scintigraphies were applied to 114 cases of parotid tumor patient. Diagnostic evaluation of these methods was estimated especially from the viewpoint of preoperative malignancy grading, comparing with their clinical figures and histopathological findings. In 99amTcO4- scintigram, parotid neoplasms often showed focal defect (81%). Otherwise, adenolymphoma actively accumulated 99mTcO4- nearly two third cases. Only mature typed adenolymphoma which comprised macroscopic follicular cyst, sometimes presented focal defect. Well differentiated type of mucoepidermoid tumors hardly presented different images from contralateral parotid glands. In 67Ga-citrate scintigram, benign neoplasms showed symmetrial or focally defective appearances (72%). On the contrally, high grade malignant tumors indicated high incidence of focal hot nodule (75%). Low grade malignancy tumors, which comprise acinic cell tumor and well differenciated mucoepidermoid tumor, also showed focal hot scintigram or diffuse increased uptake in high rate (92%). This study proved that 99mTcO4- and 67Ga-citrate scintigraphies are sufficiently useful to diagnose parotid tumor malignancy in advance to surgical operation.
一般社団法人日本耳鼻咽喉科学会の論文