Histopathological study of parotid adenolymphoma.
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概要
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Parotid adenolymphoma is composed of two histologic components; epithelial and lymphoid. Although theories regarding the histogenesis of this tumor have long been disputed, there have been no definite conclusions. The purpose of this study was to clarify the origin of the lymphoid tissue and the epithelial component of this tumor by histochemical and immuno-pathological techniques, electron microscopy and a survey of HE-stained sections.The results obtained were as follows: The characteristics of the epithelial component were similar to those of the striated ducts and the excretory ducts of the normal parotid gland. Morphological studies showed the presence of parotid ductal inclusion in the lymphnodes around the tumor. The lymphoid tissues of the adenolymphoma had many similarities to those of the normal or reacted lymphnodes. B-lymphocytic proliferation as well as increased content of IgA were evident through various immunological and immunohistochemical analyses. The absence of the myoepithelial cells in the tumor was indicated by observation of the anti-actin anti-serum-reacting cells and by electron microscopical studies.Based on these results, it was assumed that the lymphoid tissues of adonolymphoma were composed of the lymphatic tissues of the normal or reacted lymphnode, and that the origin of the epithelial component was the parotid ductal inclusion in the lymphnodes in or around the parotid gland.
- 一般社団法人 日本耳鼻咽喉科学会の論文