Caloric response of the isolated semicircular canal.

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In order to investigate the mechanism of caloric response, thermal stimuli were applied to the partially isolated semicircular canal of the bull frog. Warming or cooling stimulus to the canal side changed the ampullary nerve activity. When the semicircular canal was placed in the horizontal plane, thermal stimulus induced monophasic response, which is possibly due to a change in the density of the endolymph. When the semicicular canal was placed in the vertical plane, the responses were biphasic, which are implicated by both density change and thermoconvection flow of the endolymph. These results suggest that changes in the endolymphatic density as well as convection flow might be responsible for caloric nystagmus.
一般社団法人日本耳鼻咽喉科学会の論文