シェーグレン病におけるRIシンチグラフィの診断的意義-唾液腺造影検査, 口唇病理組織検査および眼科的検査との対比-
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概要
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Salivary gland's function of patients with Sjogren's disease and any other collagen disease (RA SLE PSS etc) were examined by sialography, lip biopsy and sialoscintigraphy. Relationship among these examination and that with KCS (kerato conjunctivitis sicca) were studied. The classification of sialogram is as follows;(-): normal(±): abnormal image without typical duct ectasis(+): terminal duct ectasis in diameter of about 1mm(++): remarkable duct ectasis with branchless tree sign(+++): remarkable duct ectasis with leak of medium from any duct 99m-Tc sialoscintigraphy: Dynamic 99m-Tc uptake curve of the salivary gland was made oncomputer and absolute uptake, inclined uptake rate of early 5 minutes and execretory rate were calculated. Then the result were obtained as follows.1) 99m-Tc sialoscintigraphy related well with other parameters. Especially absolute uptake was well correlated with the grade of sialogram and uptake was available to diagnose early stage which observed high incidence of the collagen disease.2) 99m-Tc sialoscintigraphy was useful as the examination performed without pain repeatedly.3) Among the result of examination for salivary glands and KCS, there was different tendency. So as to diagnose Sjögren's disease exactly, we have to pay attention to diagnose Sjögren's disease on the basis of single examination. Particularly in the case of KCS positive only, 99m-Tc sialoscintigraphy (especially uptake rate) was valuable.
- 一般社団法人 日本耳鼻咽喉科学会の論文